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HUMAN REPRODUCTION

SHARED DONATION

EGG DONATION

EGG DONATION

Egg donation, also called oocyte donation, consists of the anonymous and voluntary donation of eggs from one person to another so that they can be fertilized through IVF/ICSI and later transferred into the recipient’s uterus. Women and people with a uterus from the age of 35 experience a decline in their fertility potential, which is often the cause of unsuccessful assisted reproduction treatments. In these cases, egg donation may be the solution to help avoid negative outcomes in older individuals.

How does egg donation work?

EGG DONATION

Specialized fertility clinics maintain a permanent registry of donors, including general clinical information and physical characteristics, as these individuals may also have undergone IVF/ICSI treatments and produced surplus eggs that were not used. These eggs are then cryopreserved at the clinic until they are matched with a recipient undergoing treatment at the same clinic, who will use them for fertilization and embryo transfer into the uterus.

The donor and the recipient may also begin treatment simultaneously, eliminating the need to freeze the eggs. The donor undergoes ovarian stimulation, while the recipient follows a treatment to prepare the endometrium (the inner lining of the uterus) before embryo transfer. This preparation uses the hormones of the natural menstrual cycle, starting with estrogen followed by progesterone.

In both cases, the donated eggs are fertilized in the laboratory using sperm. One or two resulting embryos are then transferred to the recipient’s uterus, usually on the fifth day of development. A pregnancy test is performed 9 to 12 days later.

The success rate of this treatment is high, around 55%. The main factors contributing to this high success rate are the donor’s young age and the recipient’s endometrium, which is prepared without interference from the hormones used during ovarian stimulation.

Requirements for egg donation

● No family history of genetic diseases;
● No history of sexually transmitted infections;
● Be no older than 33 years of age;
● Physical characteristics, blood type, and Rh factor compatible with the recipient;
● No infectious or contagious diseases;
● Good ovarian reserve;
● Complete privacy, anonymity, and confidentiality;
● Maintain healthy lifestyle habits: do not smoke, avoid alcohol, get regular sleep, and eat a balanced diet.

General indications for receiving donated eggs:


  • LGBTQIAP+ couples who need donated eggs to create embryos;

  • Patients who no longer have eggs due to natural menopause or as a result of chemotherapy or radiation therapy;

  • Older patients whose eggs are of insufficient quality to produce embryos capable of implantation;

  • Patients who have not achieved success with previous in vitro fertilization attempts.

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